PERBEDAAN PROFIL LIPID DAN KADAR ASAM URAT PADA PASIEN DIABETES MELITUS TIPE II DENGAN DAN TANPA HIPERTENSI

Filliana Savitri, Intani Kurnia Savitri, Pugud Samodro, Lantip Rujito


Abstract


Diabetes Mellitus type 2 is the 7th world of death problem with the 95% proportion rate. Hypertension has also a correlation with this condition. The mortality of cardiovascular is 2-3 times over from diabetics with hypertension than diabetics with normotension which caused by lipid and aciduric disturbations. This study was conducted using cross-sectional design. Twenty-five sample of diabetics normotension and 25 sample of diabetics patient along with hypertension in Ajibarang Hospital District Banyumas and comply with inclusion-exclusion criteria were taken suing consecutive sampling. Data from the cholesterol and triglyceride total test were collected and analyzed with Mann-Whitney test. Additionally, HDL cholesterol and LDL was analyzed using T-Test.  This Study showed that average total cholesterol from diabetics along with hypertension patients was in a range of 185.16 ± 36.59 and Diabetics patient without hypertension was 196.76 ± 44.62 (p = 0,503). Besides, the average rate of triglyceride level on diabetics patient with hypertension was 181.76 ±72.68 and diabetics patient along without hypertension was 180.28 ± 125.75 (p=0,367). The average rate of HDL cholesterol level on diabetics patient with hypertension was 39.12 ± 11.07 and diabetics patient along without hypertension was 42.37 ± 14.98  (p = 0,387). In addition, Average rate of LDL level on diabetics patient with hypertension was 112.57 ± 24.77 and diabetics patient along without hypertension was 118.33 ± 37.41 (p = 0,524). The average rate of uric acid on diabetics patient with hypertension was  6,120 ± 1,45 and diabetics patient along without hypertension was 5,768 ± 2,45 (p=0,200).  As a conclusion, there is no difference with total cholesterol, triglyceride, HDL, LDL cholesterol, and uric acid significant from diabetics patient with or without hypertension in Ajibarang Hospital District Banyumas in 2016.


Keywords


Diabetes Melitus, Hipertensi, Asam urat, Profil lipid, LDL, HDL

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