SKIRINING FITOKIMIA DAN UJI ANTIAGREGASI PLATELET EKSTRAK DAUN LAMPENI (Ardisia humilis) ASAL PULAU PEUCANG TAMAN NASIONAL UJUNG KULON

Fransiska Tinambunan (1)


(1) 


Abstract


Lampeni (Ardisia humilis) is a plant that can be found in Peucang Island, Ujung Kulon National Park. Lampeni are used as medicinal plants because they can produce secondary metabolites. The purpose of this study was to determine the phytochemical content and antiaggregation platelets potential of lampeni leaf. This research was conducted in September-October 2018 on Peucang Island and UNJ Biochemistry Laboratory. The phytochemical content of the lampeni leaf was in the form of alkaloids, flavonoids, terpenoids, saponins and tannins and platelet aggregation test using the Pimentel method. Lampeni leaf extract was made using simplicia and solvent which is 1:10 (w/v) with 70% ethanol solvent.  The results of the phytochemicals content test on the lampeni leaf contain alkaloids, flavonoids, terpenoids and saponins but do not contain tannins. The results of platelet aggregation test showed there was no formation of violet gel which indicated that platelet aggregation did not occur so that the lampeni leaf had the ability as an anti-aggregate platelet.


Keywords


Lampeni, fitokimia

References


Abdullah M, Dewi M, Talitha W. 2010. Inventarisasi Jenis-Jenis Tumbuhan Berkhasiat Obat Hutan Hujan Dataran Rendah Desa Nyamplung Pulau Karimunjawa. Biosaintifika. 2(2): 75-81.

Adinata IP, Khairul A, Dewi K. 2013. Identifikasi Senyawa Metabolit Sekunder Fraksi Aktif Daun Jarak Pagar (Jatropha curcas L.) dan Uji Aktivitas Larvasida terhadap Larva Nyamuk Aedes aegypti. Jurnal Kimia Sains dan Aplikasi. 16(2): 41-45.

Amin M, Shimul B , Md. Ibrahim, Md. Mizanur, Mohammad SM, Rokaiya S , Md. Khorshed A, K.M. Rahat MJ , Shamima NA. 2015. A Study on Ardisia solanacea for Evaluation of Phytochemical and Pharmacological Properties. International Journal of Pharmacognosy and Phytochemical Research. 7(1): 8-15.

Aminah, Siti. 2016. BSA Bovine sebagai protein standart. Jurnal Ilmiah Manuntun. 2(1): 111-119.

Angelina M, Sri Hartati, Indah D, Lia M, Imaculata. 2012. Aktivitas Anti Agregasi Platelet dan Aktivitas Antitrombosis Ekstrak Etanol Daun Cinco (Cyclea barbata Miers.). Jurnal Ilmu Kefarmasian Indonesia. 10(1): 20-23.

Aragao, G. F., Cunha Pinheiro, M. C., Nogueira Bandeira, P., Gomes Lemos, T. L. and de Barros Viana, G. S. (2007). Analgesic and anti-inflammatory activities of the isomeric mixture of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) march. Journal of Herbal Pharmacotherapy. 7(2): 31-47.

Ching J, Chua TK, Chin LC, Lau AJ, Pang YK, Jaya JM, Tan CH, Koh HL. 2010. Beta-amyrin from Ardisia elliptica Thunb. Is more potent than aspirin in inhibiting collagen- induced platelet aggregation. Indian J Exp Biol. 48(3): 257-259.

Dewi RS, Ni Made Dwi S, Sulistyo R. 2017. Efek Anti-Agregasi Platelet Ekstrak Etanol Daun Salam (Syzygium polyanthum (Wight) Walp.) Pada Mencit. Ilmu Kefarmasian Indonesia. 15(1): 31-37.

Halim S. 2006. Tes Agregasi untuk Pencegahan Penyakit Kardiovaskuler. Meditek. 14(38): 37-44.

Harborne J. 1987. Metode Fitokimia: Penuntun Cara Modern Menganalisis Tumbuhan. Bandung: Penerbit ITB.

Harborne J. 1996. Metode Fitokimia: Penuntun Cara Modern Menganalisis Tumbuhan. Cetakan kedua. Penerjemah:

Patmawinata, K. dan I. Soediro. Bandung: Penerbit ITB.

Hidayah N. 2016. Pemanfaatan Senyawa Metabolit Sekunder Tanaman (Tanin dan Saponin) dalam Mengurangi Emisi Metan Ternak Ruminansia. Jurnal Sain Peternakan Indonesia. 11(2): 89-97.

Jianhong C. 2011. Chemical And Pharmacological Studies Of Ardisia Elliptica: Antiplatelet, Anticoagulant Activities And Multivariate Data Analysis For Drug Discovery, [Tesis] dipublikasikan Department Of Pharmacy National University Of Singapore (online)

Khatun A, M. Rahman, S. Kabir, M.N. Akter, S.A. Chowdhury. 2013. Phytochemical and pharmacological properties of methanolic extract of Ardisia humilis VAHL. (Myrsinaceae). IJRAP. 4(1): 38-41.

Kusumastuti SA, Firdayani, Chaidir. 2015. Potensi Ekstrak Etanol Daun Lampeni (Ardisia elliptica) dan Fraksinya Sebagai Agen Antiproliferatif Terhadap Sel Kanker Hati HEPG2. Prosiding Seminar Nasional Penelitian dan PKM Kesehatan. 1(1): 389-394.

Marce I. 2016. Uji Aktivitas Anti Agregasi Platelet dan Antitrombotik Ekstrak Etanol Daun Sukun (Arthocarpus altilis (Park.) Fosberg). [Tesis]. Yogyakarta: Universitas Gadjah Mada.

Minarno E.B. 2015. Skrining Fitokimia dan Kandungan Total Flavonoid Pada Buah Carica pubescens Lenne & K. Koch Di Kawasan Bromo, cangar dan Dataran Tinggi Dieng. El-Hayah. 5(2): 73-82.

Mustari AH. 1997. Kunjungan ke Taman Nasional Ujung Kulon. Media Konservasi. 5(2): 101-109.

Nazeh M, Zurainee MN, Marzida M, Asdren Z, Mohd Shahnaz H, Fadzly A, Mustafa K. 2017. Phytochemical constituents, antioxidant and antibacterial activities of methanolic extract of Ardisia elliptica. Asian Pac J. Trop. Biomed. 7(6): 569–576.

Pimentel SM, Zenaida P. Bojo, Amy V. D. Roberto, Jose EH. Lazaro, Gina CM, Leila M. Florentino, Pilar Lim-Navarro, Deniz T, Chris M.I., Gisela P. Concepcion. 2003. Platelet Aggregation Inhibitors from Philippine Marine Invertebrate Samples Screened in a New Microplate Assay. Marine Biotechnology. 5(4): 395-400.

Putri R, Evi U, Rini R. 2014. Uji Aktivitas Anti Platelet Ekstrak Etanol Kubis Merah (Brassica oleracea var. Capitata L.). e-Jurnal Pustaka Kesehatan. 2(1): 111-114.

Rambe, Aldy. S. 2004. Obat-Obat Penyakit Serebro Askular. Universitas Sumatera Utara.

Samsudin MA, Koirudin. 2008. Ekstraksi, filtrasi dan uji stabilitas zat warna dari kulit manggis (Garcinia mangostana). Jurnal Teknik Kimia, Fakultas Teknik Universitas Diponegoro. X(1): 1-8.


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